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This describes why 1 lorazepam dose, Irrespective of its shorter serum 50 %-life, has a lot more prolonged peak outcomes than an equivalent diazepam dose.[ninety nine] Lorazepam is rapidly conjugated at its three-hydroxy team into lorazepam glucuronide that's then excreted from the urine. Lorazepam glucuronide has no demonstrable CNS activity in an